Figure 3.
PP-2 inhibits the IL-1β-induced enhancement of the phenylephrine-induced contraction in aorta from SHRSP (A) and WKY rats (B). Results are represented as the increase in force generated from baseline, * indicates a significant difference (p<0.05) from IL-1β treated vessels. N=9 for SHRSP vessels treated with IL-1β and n=5 for SHRSP vessels treated with IL-1β and PP-2. N=6 for both groups of WKY vessels. IL-1β - interleukin 1 beta, PE - phenylephrine, SHRSP - Stroke prone spontaneously hypertensive rat, WKY - Wistar Kyoto.