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. 2007 Aug 2;8:261. doi: 10.1186/1471-2164-8-261

Table 4.

Genes that have a high confidence in congruence between protein and transcript profile during growth

Gene/spot Confidence ((1-p) × 100) Spearman rank correlation Annotated gene function
Positive correlation in set A
SCO0379:123 100 1 catalase KatA
SCO1651 100 1 conserved hypothetical protein
SCO1776 100 1 putative CTP synthetase PyrG
SCO2554 100 1 DnaJ
SCO7510 100 1 peptidyl-prolyl cis-trans isomerase CypH
Positive correlation in set B
SCO1212 100 1 putative ligase
SCO2115 100 1 putative 2-dehydro-3-deoxyphosphoheptonate aldolase AroH
SCO2539 100 1 Era-like GTP-binding protein
SCO3801 100 1 putative aminopeptidase
SCO3907 100 1 single strand DNA-binding protein ssb
SCO4809 100 1 succinyl CoA synthetase alpha chain SucD
SCO4813 97.7 0.87 phosphoribosylglycinamide formyltransferase PurN
SCO4824 98.4 0.89 bifunctional protein (methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase FolD
SCO4921 100 1 putative acyl-CoA carboxylase complex A subunit AccA2
SCO5745 100 1 conserved hypothetical protein
Positive correlation in set C
SCO0379:123 97 0.85 catalase KatA
SCO1244 98 0.88 Biotin synthase BioB
SCO1489 98.4 0.89 DNA-binding protein BldD
SCO1523 98.4 0.92 conserved hypothetical protein
SCO1651 98.4 0.89 conserved hypothetical protein
SCO1776 99.8 0.96 putative CTP synthetase PyrG
SCO2949 98 0.88 UDP-N-acetylglucosamine transferase MurA
SCO3122 98.4 0.9 putative nucleotidyltransferase
SCO4550 98.4 0.9 conserved hypothetical protein
SCO4813 97.7 0.87 phosphoribosylglycinamide formyltransferase PurN
SCO4824 98.4 0.89 bifunctional protein (methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase FolD
SCO5113 98.4 0.9 BldKB, putative ABC transport system lipoprotein,
Negative correlation (all in set C)
SCO1947:683 98.4 -0.86 glyceraldehyde-3-phosphate dehydrogenase Gap1
SCO2198:235 97.7 -0.87 glutamine synthetase I GlnA
SCO2198:746 98.8 -0.92 glutamine synthetase I GlnA
SCO2634 97 -0.85 conserved hypothetical protein
SCO2736:472 95.1 -0.83 Citrate synthase CitA
SCO5466 97.8 -0.87 putative hydrolase

Congruence across time was calculated by Spearman Rank Correlation given different data sets where set A represents 5 time points in M600, B represents 5 time points in ΔbldA and C represents 10 time points spanning both M600 and ΔbldA (the 5 time points are 1, 2, 4, 6 and 8 in Fig. 1).