Table 2.
Transcriptional Factors altered by PAR-AP stimulation of the mouse bladder mucosa as detected by Protein/DNA combo array.
| Upregulated | |
| AP-1 | Fos, FosB, Fra1, Fra2, Jun, JunB [82] |
| AP-2 | Activator protein 2 [83] |
| Brn-3 | POU4F1: POU domain, class 4, transcription factor 1 [84] |
| GAS/ISRE | Gamma-interferon activation site [85] |
| GATA-3 | GATA binding protein3 (globin transcription factor 3) [86] |
| HNF-4 | Hepatocyte nuclear factor 4 [87] |
| HOX4C | homeo box4C [88] |
| Oct-1 | POU2F1: POU domain, class 2, transcription factor 1 [89] |
| p53 | TP53: tumor protein p53 [90] |
| PBX1 | pre-B-cell leukemia transcription factor 1 [91] |
| PTF1 | pancreas specific transcription factor [92] |
| RORE | RAR-related orphan receptor [93] |
| Tax/CREB | TAX & CREB complex-responsive protein [94] |
| TFEB | TFEB is a the b-HLH-LZ closely related to TFE3 [38] |
| Thy-1 BP | Thy-1binding protein [38] |
| Down Regulated | |
| AIC, CBF | Apolipoprotein AI (ApoAI) promoter c region, CCAAT-binding factor ([95] |
| ARP | COUP-beta; apolipoprotein AI; NR2F2 ([95] |
| ATF/CRE | Activating transcription factor [96] |
| CREB2 | cyclic AMP response element binding protein 2 [97] |
| Fra-1/JUN | Fos-related antigen [98] |
| Freac-7 | Forkhead box L1 [99] |
| Gfi-1 | Growth factor independent 1 [100] |
| HFH-2 | Forkhead box D3 [101] |
| HNF-1A | Hepatocyte nuclear factor 1 [102] |
| HOXD9 | HOXD9,10 [88] |
| HSE | Heat shock transcription factor [103] |
| kBF-A | kappa immunoglobulin enhancer binding protein [104] |
| Lactoferrin BP | Lactoferrin enhancer binding region for estrogen receptor [105] |
| LF-A2 | Liver-specific transcription factor [106] |
| LXRE1 | Nuclear receptor subfamily 1, group H, member 2 [107] |
| MTF | MRE-binding transcription factor-1 [108] |
| NF-1 | CTF; NF-I; TGGCA-binding protein [109] |
| Pax2 | Pax-2 DNA-binding transcription factor [110] |
| Pax5 | Pax-5 DNA-binding transcription factor [111] |
| Snail | Zinc-finger transcription factor Snail [112] |
| T3R | c-ErbA; thyroid hormone receptor [113] |
| TEF1 | TEF 1 box [114] |
| WAPBP | Whey acidic protein binding protein [115] |