Table 4.

Top 20 elements of the 441 ones of a window of size 21 according to the Fisher's index

Rank	Position1	Type	Fisher's index
1	T	conservation index	0.987
2	C4	conservation index	0.534
3	N4	conservation index	0.469
4	N3	conservation index	0.307
5	N7	conservation index	0.306
6	C3	conservation index	0.248
7	T	L2	0.243
8	C7	conservation index	0.240
9	T	G	0.203
10	T	I	0.143
11	C8	conservation index	0.132
12	C1	conservation index	0.092
13	T	V	0.059
14	N1	conservation index	0.057
15	N4	I	0.057
16	N4	G	0.056
17	T	F	0.053
18	T	S	0.052
19	N8	conservation index	0.045
20	N4	L	0.041

¹T: the target residue, C4: the 4th residue C terminal to the target residue, N4: the 4th residue N terminal to the target residue. Thus, the conservation index of the target residue is most indicative of its burial status, and the conservation index of the 4th residue C terminal to the target residue is second most indicative of the burial status of the target residue.

²L: leucine, G: glycine, I: isoleucine, V: valine, F: phenylalanine and S: serine.