Table 3 Cost‐effectiveness results.
Time delay | Strategy | Mean costs (£) | Mean QALYs | ICER (£) | Probability of being cost effective for threshold of: | ||
---|---|---|---|---|---|---|---|
£10 000 | £20 000 | £30 000 | |||||
Base‐case analysis | |||||||
Average delay (54 min) | Primary angioplasty | 12 760 | 7.12 | 9 241 | 0.55 | 0.90 | 0.95 |
Thrombolysis | 10 080 | 6.83 | – | 0.45 | 0.10 | 0.05 | |
Time delays of: | |||||||
30 Minutes | Primary angioplasty | 12 820 | 7.23 | 6 850 | 0.82 | 0.98 | 0.99 |
Thrombolysis | 10 080 | 6.83 | – | 0.18 | 0.02 | 0.01 | |
60 Minutes | Primary angioplasty | 12 750 | 7.09 | 10 269 | 0.43 | 0.83 | 0.91 |
Thrombolysis | 10 080 | 6.83 | – | 0.57 | 0.17 | 0.09 | |
90 Minutes | Primary angioplasty | 12 670 | 6.87 | 64 750 | 0.13 | 0.36 | 0.45 |
Thrombolysis | 10 080 | 6.83 | – | 0.87 | 0.64 | 0.55 | |
Differential length of hospital stay* | |||||||
Average delay (54 min) | Primary angioplasty | 12 030 | 7.12 | 5 448 | 0.82 | 0.95 | 0.97 |
Thrombolysis | 10 450 | 6.83 | – | 0.18 | 0.05 | 0.03 | |
30 Minutes | Primary angioplasty | 12 085 | 7.23 | 4 087 | 0.95 | 0.99 | 0.99 |
Thrombolysis | 10 450 | 6.83 | – | 0.05 | 0.01 | 0.01 | |
60 Minutes | Primary angioplasty | 12 020 | 7.09 | 6 038 | 0.75 | 0.91 | 0.99 |
Thrombolysis | 10 450 | 6.83 | – | 0.25 | 0.09 | 0.01 | |
90 Minutes | Primary angioplasty | 11 940 | 6.87 | 37 250 | 0.32 | 0.47 | 0.52 |
Thrombolysis | 10 450 | 6.83 | – | 0.68 | 0.53 | 0.48 |
ICER, incremental cost‐effectiveness ratio; QALYs, quality‐adjusted life years.
*Using an estimate of 5.8 days (SE 1.6) for primary angioplasty and 12.1 days (SE 2.9) for thrombolysis (Morgan K, personal communication, 2005).