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. 1997 Mar 4;94(5):1872–1877. doi: 10.1073/pnas.94.5.1872

Figure 4.

Figure 4

Model for retroposon integration in mammals. (a) Enzymatic nicking in the presence of RNA indicated by a vertical black arrow. (b) Synthesis of cDNA, indicated by a dotted line, and formation of the second nick, indicated by a black arrow pointed down. (c) Completion of the reverse transcription and DNA-dependent DNA synthesis, indicated by a dashed line and the lowercase letters, followed by ligation. (d) Elimination of RNA and synthesis of the second DNA strand. Modified after Luan et al. (19).