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. Author manuscript; available in PMC: 2007 Oct 5.
Published in final edited form as: Arch Biochem Biophys. 2006 Aug 22;454(1):42–54. doi: 10.1016/j.abb.2006.08.003

Figure 4.

Figure 4

Midazolam (A) 1′- and (B) 4-hydroxylation kinetics by CYP3A4. ●, ▲, ∎, ▼ and ◆ represent wild-type, C98A, C98S, C98F and C98W, respectively. All lines through experimental data points are the fit to the Michaelis-Menten equation.