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. Author manuscript; available in PMC: 2007 Oct 6.
Published in final edited form as: Bioorg Med Chem. 2007 Mar 13;15(11):3825–3831. doi: 10.1016/j.bmc.2007.03.025

Table 1.

Stern-Volmer constants for single-stranded (SS), double-stranded (DS), A-site (AS) RNAs and with paromomycin and neamine.

RNA aminoglycoside Ksv (M−1)
SS none 32.1 ± 2.0
DS none 4.2 ± 0.5
none 18.6 ± 0.5
1 μM paromomycin 34.6 ± 1.6
AS 10 μM paromomycin 48.7 ± 0.2
100 μM paromomycin 75.9 ± 10.7
10 μM neamine 15.6 ± 0.8
AS 100 μM neamine 15.3 ± 1.3
1 μM neamine 11.7 ± 1.7