Table 1.
Mean arterial pressures before (LTF), during and after (recovery) CO2 tests with and without PEEP.
| Time Control | Sustained Hypoxia | Intermittent Hypoxia | ||||
|---|---|---|---|---|---|---|
| CO2 Test | non-PEEP | PEEP | non-PEEP | PEEP | non-PEEP | PEEP |
| Hypercapnia | ||||||
| LTF | 104.3 ± 3.8 (3) | 96.0 ± 1.5 (3) | 101.3 ± 7.3 (4) | 92.0 ± 5.9 (4) | 115.3 ± 2.3 (4) | 104.2 ± 5.8 (5) |
| 5% CO2 | 110.7 ± 4.7 (3) | 97.7 ± 4.3 (3) | 105.0 ± 8.7 (4) | 93.0 ± 4.8 (4) | 119.5 ± 4.8 (4) | 109.0 ± 4.6 (5) |
| Recovery | 105.0 ± 4.6 (3) | 96.7 ± 1.7 (3) | 102.8 ± 8.0 (4) | 92.3 ± 6.6 (4) | 116.5 ± 3.9 (4) | 106.4 ± 8.4 (5) |
| LTF | 105.3 ± 5.4 (3) | 95.7 ± 3.8 (3) | 105.5 ± 8.4 (4) | 97.5 ± 11.9 (4) | 111.0 ± 6.2 (5) | 101.0 ± 4.4 (5) |
| 10% CO2 | 117.3 ± 6.7 (3) | 103.7 ± 5.2 (3) | 123.0 ± 11.5 (4) | 106.3 ±11.9 (4) | 130.2 ± 8.9 (5) | 116.6 ± 3.0 (5) |
| Recovery | 108.0 ± 6.1 (3) | 94.3 ± 2.9 (3) | 109.5 ± 8.3 (4) | 97.8 ± 9.9 (4) | 113.8 ± 6.1 (5) | 101.8 ± 4.5 (5) |
| Hypocapnia | ||||||
| LTF | 109.8 ± 4.9 (4) | 102.8 ± 11.3 (4) | 103.5 ± 4.7 (4) | 95.8 ± 2.2 (4) | 105.5 ± 6.4 (4) | 94.8 ± 1.4 (5) |
| Low CO2 | 102.8 ± 5.0 (4) | 91.0 ± 10.9 (4) | 99.0 ± 4.2 (4) | 87.5 ± 1.3 (4) | 102.8 ± 5.4 (4) | 88.2 ± 1.5†‡ (5) |
| Recovery | 108.0 ± 5.1 (4) | 104.8 ± 12.2 (4) | 103.3 ± 4.5 (4) | 95.3 ± 1.6 (4) | 105.5 ± 5.9 (4) | 94.6 ± 1.5 (5) |
| LTF | 108.0 ± 5.1 (4) | 103.3 ± 12.7 (4) | 98.0 ± 4.5 (4) | 90.3 ± 4.1 (4) | 103.3 ± 3.8 (7) | 92.7 ± 2.0† (7) |
| apnea | 98.3 ± 9.8 (4) | 55.0 ± 14.6†‡ (4) | 92.0 ± 3.4 (4) | 38.3 ± 6.9†‡ (4) | 93.3 ± 5.3 (7) | 45.6 ± 1.7†‡ (7) |
| Recovery | 107.0 ± 4.6 (4) | 100.8 ± 12.5 (4) | 100.3 ± 4.2 (4) | 89.3 ± 3.8 (4) | 101.5 ± 3.7 (7) | 91.9 ± 2.9 (7) |
Data are means ± SE (number of rats), in mmHg.
†
indicates significant difference from non-PEEP
‡
indicates significant difference from LTF and recovery.