Table 1.

Significant clusters in the two-sample t-tests comparing default mode functional connectivity in MD subjects versus controls. Height and extent thresholds of p < 0.01 were used to determine significant clusters.

Cluster anatomical locations (Brodmann's area)	Cluster size(voxels)	Maximal z-score primary peak	Primary peak location
MD versus Controls
Thalamus	170	4.48	4, −20, 5
Subgenual cingulate (25)	104	3.64	−10, 5, −10
Medial Prefrontal/Orbitofrontal (11)	82	3.63	14, 42, −17
Cuneus/Precuneus (19)	89	3.36	2, −86, 37
Controls versus MD
No significant clusters