. Author manuscript; available in PMC: 2007 Nov 1.

Published in final edited form as: Hematol Oncol Clin North Am. 2007 Aug;21(4):609–v. doi: 10.1016/j.hoc.2007.06.003

Table 1.

Common clinical and laboratory features of TTP.

Thrombocytopenia (platelet count <20×10⁹/L in acute cases)

Microangiopathic hemolytic anemia

Neurologic abnormality or complaint

Renal abnormalities

Proteinuria and microscopic hematuria

Peak BUN ≤ 0.4 g/L or Cr ≤ 0.03 g/L

Fever ≥ 38.3°C

Microthrombi on tissue biopsy

Exclusion

Evidence of intravascular coagulation

Evidence of underlying condition associated with or producing microangiopathic syndrome

Positive antinuclear antibody, anti-DNA antibody, or LE preparation

Oliguria or anuria

Modified from Bukowski [66].