Table 2.

Heterogeneity in diagnosis of TTP

Authors	Year	No.	Exclusion of renal failure	Exclusion of secondary cases	Severe deficiency	ADAMTS13
Furlan, et al	1998	24	Yesa	No	83%
Tsai, et al	1998	39	Yesb	Yesc	100%
Veyradier, et al	2001	111	Yesa	No	71%
Rick, et al	2002	50	Not stated	Not stated	78%
Bohm, et al	2002	22	Not stated	No	91%
Vesely, et al	2003	48	No	Yesd	33%
Hovinga, et al	2004	396	Not stated	Not stated	57%
Peyvandi, et al	2004	100	No	No	48%
Zhou, et al	2004	34	Yesb	Yesc	100%
Coppo, et al	2004	46	No	Yes	67%
Zheng et al	2004	37	No	No	43%
Kokame, et al	2005	41	Not stated	Not stated	80%
Terrel, et al	2005	70	No	Yesd	34%
Matsumoto, et al	2005	108	Not stated	Yesa	52%

^aBased on referral diagnosis

^bCr_max >4.0 g/dL

^cBased on overall course

^dBased on initial assessment