Table 4. Effect of syntenin knock down on clonal growth of keratinocytes.
Keratinocytes were transduced with empty retroviral vector (WT), DeltaFl or DeltaDS in combination with syntenin RNAi (Rnai) or scrambled RNAi control sequence (Ctrl). Data are mean ± s.d. of triplicate dishes from at least 3 experiments.
| CFE | % Abortive clones | |
|---|---|---|
| WT+Ctrl | 26.1 ± 3.2 | 27.1 ± 3.9 |
| WT+Rnai1 | 25.8 ± 4.4 | 28.2 ± 3.2 |
| FL+Ctrl | 28.3 ± 3.2 | 22.5 ± 7.9 |
| FL+Rnai1 | 16.6 ±1.4 | 57.8 ± 8.1 |
| DS+Ctrl | 22.1 ± 0.7 | 30.5 ± 5.1 |
| DS+Rnai1 | 23.1 ± 1.1 | 32.4 ± 5.9 |