Table 1. Subject characteristics.
CON (n=617) | HTN (n=719) | HfnlEF (n=244) | |
---|---|---|---|
Age (range), years | 57 (45–96) | 66 (46–91)* | 76 (22–99) *† |
Males, % | 45 | 44 | 45 |
Height, cm | 169±10 | 167±10* | 165±13* |
Weight, kg | 73±13 | 84±19* | 86±25* |
Body surface area, m2 | 1.85±0.21 | 1.96±0.26* | 1.97±0.31* |
Body mass index, kg/m2 | 25.4±2.7 | 29.8±5.9* | 32.2±20.7*† |
Hypertension, % | 0 | 100* | 96* |
Coronary artery disease, % | 0 | 16* | 53*† |
Diabetes mellitus, % | 0 | 11* | 37*† |
Glomerular filtration rate, ml/min/1.73m2 | 74.4±14.1 | 74.7±37.0 | 64.3±28.1*† |
BNP (Shionogi), pg/ml | 20.0±40.3 | 30.5±45.2* | 260.7±330.2*† |
Log BNP (Shionogi, pg/ml) | 1.06±0.41 | 1.23±0.46* | 2.15±0.55*† |
Ejection fraction, % | 63±5 | 65±6 | 62±6*† |
Heart rate, bpm | 65±10 | 67±12 | 71±15*† |
Systolic blood pressure, mmHg | 118±12 | 143±21* | 132±23*† |
Diastolic blood pressure, mmHg | 70±8 | 76±11* | 67±14† |
Pulse pressure, mmHg | 48±11 | 67±18* | 65±20* |
Data are mean ± SD unless otherwise stated. Unadjusted analysis.
p<0.05 vs CON;
p<0.05 vs HTN
BSA, body surface area; BNP, B-type natriuretic peptide