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. 2006 Nov 6;7:490. doi: 10.1186/1471-2105-7-490

Table 2.

Comparison of native formats and their HOBIT XML counterparts

Sequence formats
FASTA SequenceML simple sequence information for nucleic and amino acids
GCG SequenceAnnotationML sequence information with additional facilities for annotations
STADEN

Sequence alignment formats

FASTA AlignmentML (multiple) alignments for nucleic and amino acids
CLUSTAL
MSF

RNA secondary structure formats

mFOLD RNAStructML RNA secondary structure information
Vienna style DotBracket

RNA Secondary Structure Alignment Formats

aligned Vienna style DotBracket RNAStructAlignmentML (multiple) alignments of RNA secondary structures

The table shows a comparison of some native bioinformatic file formats (first column) and their HOBIT XML counterparts (second column). These XML formats cover sequence, alignment, RNA secondary structure and RNA secondary structure alignment formats in a form that is independent of any specific program. The usage of the XML formats leads to a significant decrease in the number of necessary file formats.