Table 2.
mRNA distribution of NY-ESO-1 in normal human tissues
| Tissue | mRNA | Tissue | mRNA |
|---|---|---|---|
| Esophagus | − | Adrenal | − |
| Brain* | − | Pancreas | − |
| Fetal brain | − | Seminal vesicle | − |
| Heart | − | Placenta | − |
| Lung | − | Thymus | − |
| Liver | − | Lymph node | − |
| Spleen | − | Tonsil | − |
| Kidney | − | Peripheral blood lymphocyte | − |
| Stomach | − | Peripheral blood lymphocyte activated† | − |
| Small intestine | − | Melanocytes | − |
| Colon | − | Thyroid | − |
| Rectum | − | Uterus | ±‡ |
| Breast | − | Testis | + |
| Skin | − | Ovary | + |
| Bladder | − | ||
*
Specimens from several different regions tested.
†
With interleukin 2 and phytohemagglutinin.
‡
Weakly positive in some specimens, negative by Northern blot analysis (see Fig. 2).