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Acid feeding increases PEPCK mRNA in Tg/Tg:ETB+/+ and Tg/Tg:ETB–/– mice. Tg/Tg:ETB+/+ and Tg/Tg:ETB–/– mice were fed control or acid diets for 7 days. PEPCK mRNA abundance was measured on total renal cortical RNA by northern blot and normalized for 18S rRNA abundance. C, control; A, acid. Tg/Tg:ETB+/+, n = 3. Tg/Tg:ETB–/–, n = 5.
