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. 2001 Jun 15;107(12):1571–1580. doi: 10.1172/JCI11941

Figure 4.

Figure 4

Z-score histograms demonstrate similar distributions of GH values in data sets obtained from randomly timed blood sampling (F+/+, M+/+, F–/–, and M–/–) or from serial blood sampling in cannulated mice (F [ICR] and M [ICR]). The GH profiles (n = 97–107 independent measurements per group) were approximated as standard normal distributions using a Z-transformation. The top four panels are the Z scores calculated for the GH data in Figure 3c. The bottom two panels are the Z scores calculated from the pulsatile GH profiles of wild-type ICR mice in Figure 1 by MacLeod et al. (35). The Z scores are grouped into bin sizes equal to 1 SD of the normalized mean for each group. The bell curve in each panel illustrates the probability of the standard normal distribution in comparison to the Z scores calculated from the experimental data.