Figure 3.

Dose-dependent suppression of infectious RSV by the 2–5A-antisense species, spA₄-antiRSV3′-3′T/(8281–8299) in comparison to the effect of spA₄-scramble3′-3′T/(8281–8299). (A) Viral plaque assays of CV-1 indicator cells was performed using RSV harvested from infected 9HTE cells that were untreated or treated with different amounts of spA₄-antiRSV3′-3′T/(8281–8299) or spA₄-scramble3′-3′T/(8281–8299) as described. The doses of oligonucleotides and the dilutions of the crude preparations of RSV that were added to the indicator cells are shown. (B) Graph of the data from A. •, spA₄-antiRSV3′3′T(8281-8299); ○, spA₄-scramble3′3′T(8281-8299).