Figure 2.

Mean (+ SEM) prostate weight (mg) in 8-month-old male mice produced by mothers implanted s.c. with Silastic capsules containing 0, 25, 100, 200, or 300 μg of estradiol from day 13 to day 19 of pregnancy. The free serum estradiol concentration (in pg/ml) in male fetuses on gestation day 18 in response to these doses of estradiol (controls = 0.21 pg/ml) is shown in relation to adult prostate weight. Group means that differed significantly are indicated by different letters, while groups with the same letter did not differ significantly.