Table 2.
Animal | Vl, ml | VV(s,L), ml·ml−1 | V(c), ml | S(a), cm2 | V(c)/S(a), ml·m−2 | τt, μm | τhb, μm | DlO2* |
---|---|---|---|---|---|---|---|---|
Mole rats | 7.50 ± 0.33 | 0.210 ± 0.0074 | 0.901 ± 143 | 6406 ± 677 | 1.483 ± 0.242 | 1.040 ± 0.083 | 0.630 ± 0.042 | 0.026 ± 0.002† |
(7.16–8.43) | (0.194–0.223) | (0.654–1.287) | (4932–8099) | (0.829–1.979) | (0.875–1.244) | (0.548–0.738) | (0.021–0.032) | |
White rats | 7.01 ± 0.18 | 0.194 ± 0.0124 | 0.719 ± 0.068 | 5378 ± 165 | 1.371 ± 0.125 | 1.228 ± 0.079 | 0.770 ± 0.068 | 0.018 ± 0.001 |
(6.72–7.46) | (0.162–0.221) | (0.569–0.857) | (5044–5835) | (1.068–1.666) | (1.077–1.454) | (0.666–0.96) | (0.016–0.021) |
Values indicate means ± SEM (n = 4 animals per group). Numbers in parentheses indicate range of data points. Data were collected as given in Materials and Methods. VL, lung volume; VV(s,L), septum volume per lung volume; Vc, volume of capillaries per lung; Sa, alveolar surface area per lung; Vc/Sa, capillary loading; τt, arithmetic mean tissue thickness; τhb, harmonic mean tissue thickness between alveolar surface and erythrocytes; and DlO2, pulmonary oxygen diffusing capacity.
Expressed in ml of O2 per sec per mmHg.
Significantly different from white rat (P < 0.05).