Table 6.

Effect of anti-FGF antibodies on angiogenin-stimulated [³H]thymidine incorporation in human endothelial cells

Antibody	Cells
	HUVE		HME
	[3H]thymidine incorporation, cpm	% increase	[3H]thymidine incorporation, cpm	% increase
Control
−	4,400 ± 200	100	9,700 ± 300	100
+	5,900 ± 50	134	12,000 ± 300	124
aFGF IgG
−	5,100 ± 100	100	10,500 ± 400	100
+	5,800 ± 100	114	12,100 ± 500	115
bFGF IgG
−	3,400 ± 600	100	5,900 ± 300	100
+	4,100 ± 500	121	7,500 ± 400	127
aFGF IgG plus
bFGF IgG
−	3,000 ± 200	100	5,900 ± 800	100
+	3,900 ± 100	130	8,100 ± 400	137

HUVE and HME cells were plated at 1.6 × 10⁴ cells per well in 24-well plates (8 × 10³ cells per cm²). Concentrations of angiogenin, anti-aFGF, and anti-bFGF antibody were 1, 10, and 10 μg/ml, respectively. −, Absence of angiogenin; +, presence of angiogenin.