Table 2.
Relation between drug use and falls in previous 12 months in 3742 UK women aged 60-79 years. Values are crude or fully adjusted* odds ratios (95% confidence interval)
Any falls (n=640) vs no falls (n=3102)
|
Two or more falls (n=265) vs no falls (3102)
|
Falls where medical attention was given (n=246) vs no falls (n=3102)
|
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Type of drug | Crude | Fully adjusted | Crude | Fully adjusted | Crude | Fully adjusted |
Hypnotics and anxiolytics | 1.94 (1.41 to 2.68) | 1.41 (1.00 to 1.98) | 2.65 (1.76 to 3.98) | 1.74 (1.11 to 2.70) | 1.28 (0.73 to 2.25) | 0.85 (0.46 to 1.57) |
Antidepressants | 2.02 (1.58 to 2.59) | 1.53 (1.15 to 2.02) | 2.83 (2.03 to 3.94) | 1.89 (1.30 to 2.76) | 1.93 (1.33 to 2.80) | 1.35 (0.89 to 2.05) |
Any central nervous system drug | 1.49 (1.34 to 1.66) | 1.25 (1.11 to 1.41) | 1.81 (1.57 to 2.08) | 1.43 (1.22 to 1.68) | 1.48 (1.26 to 1.74) | 1.26 (1.05 to 1.52) |
Analgesics | 1.25 (1.01 to 1.55) | 1.00 (0.79 to 1.25) | 1.51 (1.14 to 2.00) | 1.20 (0.87 to 1.65) | 1.08 (0.77 to 1.51) | 0.95 (0.66 to 1.36) |
Any cardiovascular drug | 1.11 (1.04 to 1.18) | 0.96 (0.89 to 1.05) | 1.24 (1.14 to 1.34) | 0.99 (0.88 to 1.11) | 1.05 (0.95 to 1.15) | 0.90 (0.79 to 1.02) |
Any endocrine system drug | 1.13 (0.96 to 1.33) | 0.95 (0.77 to 1.18) | 1.22 (0.97 to 1.54) | 0.80 (0.58 to 1.11) | 1.17 (0.92 to 1.50) | 1.02 (0.74 to 1.40) |
Any respiratory system drug | 1.09 (0.96 to 1.23) | 0.91 (0.78 to 1.06) | 1.21 (1.03 to 1.42) | 1.03 (0.84 to 1.25) | 1.13 (0.94 to 1.35) | 0.98 (0.79 to 1.21) |
Adjusted for age, body mass index, haemoglobin concentration (continuous variables), circulatory disease, diabetes, thyroid disease, asthma or bronchitis, depression, cataract or glaucoma, arthritis, heavy alcohol consumption (binary variables), and adult social class (I, II, III non-manual, III manual, IV, V) (indicator variable).