A New Anti-oestrogenic Agent in Late Breast Cancer: An Early Clinical Appraisal of ICI46474

. 1971 Jun;25(2):270–275. doi: 10.1038/bjc.1971.33

PMCID: PMC2008453 PMID: 5115829

Abstract

An introductory clinical trial of the anti-oestrogenic agent IC146474 in late or recurrent carcinoma of the breast is described.

Forty-six patients have been treated, of whom 10 have shown a good response. This is of the same order as that seen with oestrogens and androgens.

The particular advantage of this drug is the low incidence of troublesome side effects.

These references are in PubMed. This may not be the complete list of references from this article.

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