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. 2007 Sep 3;8:327. doi: 10.1186/1471-2105-8-327

Figure 1.

Figure 1

The protocol of automated polyketide annotation for a genome. ASMPKS searches microbial genome sequences for modular PKSs. It detects PKS clusters producing known polyketides by measuring the homology between protein sequences of an annotated genome and all PKS sequences, and predicts unknown gene clusters to produce putative polyketide candidates by identifying domains.