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. 2001 Sep 15;108(6):817–829. doi: 10.1172/JCI12067

Figure 6.

Figure 6

TEM of wild-type and null aged alveolar interstitium. (a) Uniformly parallel collagen bundles and diffusely staining elastin fibers (dark areas) in a heterozygotic animal at 17 months of age (scale bar, 500 nm). (b) Disorganized collagen bundles (arrowhead) but an intact basement membrane (arrows) are evident in null littermate (scale bar, 2 μm). (c) High magnification of disorganized collagen fibers (arrowhead) in independent null littermate (scale bar, 500 nm). (d) Higher magnification of area shown in b. Arrows identify intact basement membrane (scale bar, =500 nm).