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. 2001 Sep 15;108(6):817–829. doi: 10.1172/JCI12067

Figure 8.

Figure 8

Northern blot analysis of heart, kidney, and lung mRNA. We did not observe enhanced abundance of either Timp-2 or Timp-4 mRNAs in this investigation in any tissue at either 2 months or in lungs from aged animals. The Timp-1 mRNA was not detected in this experiment. The transcript encoding Collagen type-I appears to be upregulated in the heart and kidney at 2 months of age. Collagen type-IV mRNA appears to be upregulated in the aged null lung. The 18S control shows approximately equal loading between samples.