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. 2001 Oct 1;108(7):1051–1059. doi: 10.1172/JCI12467

Figure 3.

Figure 3

Effect of mechanical stimulation on 5-HT release from guinea pig small intestine (a) and human BON cells without (b) and with somatostatin-14 (c). Tissues and cells were maintained in a static condition (0 rpm; control) or exposed to mechanical stimulation ranging from 50 to 100 or 150 to 250 rpm for 20 minutes at 37°C. Values represent 5-HT release relative to controls in picomoles per well per 20 minutes. (b) Cells 0.8 ± 0.08. (c) Cells 1.3 ± 0.1. (a) Tissue 9.8 ± 4. Increasing rpm resulted in rpm-dependent increase in 5-HT release (n = 32, 0 rpm; n = 4, 50 rpm; n = 10, 60 rpm; n = 6, 80 rpm; n = 16, 100 rpm). *P < 0.05 versus 0 rpm.