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Bone marrow B lymphocyte populations in chimeric mice in an androgen-deficient state (open bars) and after androgen administration (filled bars). Tfm→C57 animals (left side) have AR expressed in marrow stroma but not in lymphoid cells; C57→Tfm animals (right side) have AR expressed in lymphoid cells but not in stroma. Exogenous androgens suppress B cell populations only in the presence of AR+ stroma in vivo.
