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Serum IgG and IgM levels were increased in PPARγ+/– mice. Serum IgG (a) and IgM (b) levels in PPARγ+/– mice (closed column, +/–) were higher than in wild-type mice (open column, +/+). Both PPARγ+/– and wild-type 12-week-old mice were bled, and serum IgG and IgM levels were measured by ELISA. The mean Ab titers (± SD) of each group of ten mice are shown. The statistical differences between PPARγ+/– and PPARγ+/+ littermates derived from the same litter were significant (*P < 0.01).
