Skip to main content
. 2001 Dec 1;108(11):1589–1596. doi: 10.1172/JCI13256

Figure 6.

Figure 6

Expression of I-Ab–Eα52-68 complex on the vascular endothelium of peripheral nerves from disease-affected H3 TKO mice. (a and b) Serial sciatic nerve sections from affected H3 TKO mice with peripheral neuritis were stained with YAe (a, green) and Y3P (b, green). (c) Fresh-frozen sections from affected H3 TKO mice including the dorsal and ventral roots of the spinal nerve (DR and VR) and the spinal cord (SC) were stained with YAe (green) and anti-CD4 mAb (red). (d) Sciatic nerve sections from B2L→H3 chimeras inoculated with H3 TKO CD4+ T cells were stained with YAe (green) and anti-CD4 mAb (red). (e) Sciatic nerve sections from H3→B2L chimeras were stained with YAe (green) and anti-CD4 mAb (red). The I-Ab–Eα52-68 complex is not expressed in the vascular walls (arrow). Each fluorescence image was superimposed on the phase-contrast image of the same field (a–e). The scale bar represents 100 μm in a and b, 80 μm in c, and 25 μm in d and e.