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. 2001 Dec 1;108(11):1717–1722. doi: 10.1172/JCI13288

Figure 2.

Figure 2

Effects of genetic disruption of the apoA-I gene or probucol treatment on the fertility of female SR-BI KO mice. Wild-type males were mated with female SR-BI KO (n = 13, black bars, average litter size = 1, 2- to 6-month mating), SR-BI/apoA-I KO (n = 17, dark gray bars, average litter size = 2.2, 4-month mating), probucol-fed SR-BI KO (n = 14, light gray bars, average litter size = 5.7, 1- to 2-month mating), and probucol-fed wild-type (n = 9, white bars, average litter size = 5.3, 1- to 2-month mating) mice. (a) Fertility expressed as percentage of females producing litters. (b) Average number of pups delivered per month per female mated (error bars represent SEM).