Table 2.
Hours post-injection | 0–2 | 2–4 | 4–6 | 6–8 | |
PS | NaCl | 3.4 ± 0.8 | 5.6 ± 1 | 10.8 ± 2.1 | 10.7 ± 2.1 |
0.02 μg | 8 ± 2 * | 11 ± 0.6 * | 13.1 ± 2.1 | 9.4 ± 4.3 | |
0.2 μg | 10.1 ± 2.3 ** | 12.2 ± 2.6 * | 15.6 ± 2.6 | 19.4 ± 3.3 * | |
1 μg | 9.3 ± 2.2 ** | 12.5 ± 3.2 * | 13.3 ± 2.4 | 11.3 ± 2.6 | |
5 μg | 5 ± 0.8 | 12.2 ± 2.3 ** | 12.4 ± 3.1 | 11.5 ± 2.4 | |
10 μg | 5.8 ± 2.3 | 9.5 ± 1.5 | 10.8 ± 3.1 | 10.7 ± 3.2 | |
SWS | NaCl | 23.5 ± 4.4 | 39.1 ± 4.8 | 43 ± 5.2 | 44.7 ± 5.6 |
0.02 μg | 34.9 ± 5.8 | 34.6 ± 2.5 | 49.1 ± 2.1 | 39.3 ± 5.2 | |
0.2 μg | 39.8 ± 3.8 * | 45.1 ± 7.3 | 51 ± 7.1 | 55.6 ± 7 | |
1 μg | 40.7 ± 7.1 * | 59.2 ± 8.4 * | 61.7 ± 4.6 * | 56.6 ± 5.9 | |
5 μg | 26.8 ± 5 | 45.9 ± 6.4 | 46.7 ± 7.2 | 40.8 ± 4.1 | |
10 μg | 37.2 ± 7.8 | 55.4 ± 11.7 | 57.3 ± 3.4 | 51.1 ± 4.7 | |
W | NaCl | 93.5 ± 4.7 | 74 ± 5.4 | 66.9 ± 6.8 | 64.7 ± 7.3 |
0.02 μg | 77.1 ± 7.8 | 74.5 ± 2.4 | 57.8 ± 2.3 | 71.3 ± 9.5 | |
0.2 μg | 70.1 ± 6 ** | 62.6 ± 7.6 | 53.3 ± 9.3 | 45 ± 9.7 | |
1 μg | 70.1 ± 8.6 * | 48.3 ± 9 * | 45 ± 5.2 * | 52.1 ± 7.8 | |
5 μg | 91.4 ± 6.7 | 63.1 ± 7.4 | 59.7 ± 10.1 | 68.3 ± 5.7 | |
10 μg | 74.8 ± 10.6 | 55.2 ± 10.8 | 49.4 ± 2.4 | 56.5 ± 6.8 |
The quantities (mean ± SEM) of PS, SWS, and W following NaCl or MCH administrations are reported in minutes per 2 hours. Significance values indicated for individual points compared to NaCl are * p < 0.05 and ** p < 0.01.