TABLE 3.
In vivo-expressed gene candidates discovered by IVIAT in V. vulnificus
| Putative protein function and identified clone | Homologous protein in database (organism [% identity]) |
|---|---|
| Signaling | |
| Vv-Ive-1 | MCP VC0906 (V. cholerae [30]) |
| Vv-Ive-2 | GGDEF-containing protein STM3388 (S. enterica serovar Typhimurium LT2 [32]) |
| Vv-Ive-3 | Putative serine/threonine protein kinase STM2520 (S. enterica serovar Typhimurium LT2 [45]) |
| Biosynthesis and metabolism | |
| Vv-Ive-4 | Uridylate kinase (UMP kinase) PyrH VC2258 (V. cholerae [77]) |
| Vv-Ive-5 | AICAR transformylase/IMP cyclooxygenase PurH VC0276 (V. cholerae [92]) |
| Vv-Ive-6 | Putative acetohydroxyacid isomeroreductase IlvC VC0162 (V. cholerae [80]) |
| Secretion | |
| Vv-Ive-7 | Sec-independent protein translocase TatB VC0087 (V. cholerae [76]) |
| Vv-Ive-8 | PAS factor, a protein secretion factor (V. alginolyticus [85]) |
| Transcriptional activator | |
| Vv-Ive-9 | LysR-type transcriptional regulator IlvY VC0161 (V. cholerae [43]) |
| Vv-Ive-10 | Transcriptional activator HlyU VC0678 (V. cholerae [64]) |
| Known hypothetical protein | |
| Vv-Ive-11 | Putative lipoprotein gene YaeC VC0905 (V. cholerae [74]) |
| Vv-Ive-12 | Conserved hypothetical protein VC1606 (V. cholerae [56]) |