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Effect of the in vivo-expressed gene mutation on the LD50 of V. vulnificus
| Strain | Genotype | LD50 (CFU/mouse) | Fold increase in LD50 |
|---|---|---|---|
| MO6-24/O | V. vulnificus WT, a clinical isolate | 4.0 × 106 | |
| CMCP6 | V. vulnificus WT, a clinical isolate | 3.6 × 105 | |
| CMM1704 | MO6-24/O with the mutation in pyrH homolog (Vv-Ive-4) | 5.5 × 107 | 14 |
| CMM1710 | MO6-24/O with the mutation in hlyU homolog (Vv-Ive-10) | 2.1 × 108 | 53 |
| CMM1705 | CMCP6 with the mutation in purH homolog (Vv-Ive-5) | 8.0 × 106 | 22 |
