TABLE 2.
Effect of different inhibitors on invasion of HEp-2 cells by L. lactis(pLM1) that expresses M1 protein on its surfacea
| Inhibitor (concn) | % Inhibition |
|---|---|
| None | 0.0 |
| Cytochalasin D (500 nM) | 100.0 |
| Staurosporine (1 μM) | 98.8 |
| Genistein (250 μM) | 1.3 |
| CalphostinC (250 nM) | 3.0 |
| Bisindolylmaleimide (50 nM) | 1.6 |
| Wortmannin (100 nM) | 92.0 |
| LY294002 (50 μM) | 84.8 |
a
Inhibitors were preincubated with cells for 30 min, and invasion was performed in the presence of inhibitors for 2 h. Results are the average of three individual experiments. Percent inhibition is calculated as described in Table 1, footnote a.