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Deduced amino acid sequence from the nucleotide sequence of murine DNA-PKcs gene. The phosphatidylinositol 3-kinase (PI3K) motifs are indicated with solid bars. Tyr-4046 is indicated by an arrow, which is terminated in the SCID DNA-PKcs gene (see also Fig. 4). The leucin zipper motif is conserved (asterisks). The box indicates the potential recognition sites of CPP32 (apopine) (31, 32).
