FIG. 4.

Activation of mo-DC by N. meningitidis OM promotes cytokine production by primed naive T cells. Allogeneic CD4⁺ CD45⁺ naive T cells were cocultured with mo-DC preexposed for 24 h to the optimal 1-μg/ml concentration of OM from the parent H44/76 strain (OM) or from the LPS-deficient mutant (pLAK-OM). Results are presented as mean cytokine production ± SE from experiments done with mo-DC from three different donors.