TABLE 2.
Patient characteristics
| Condition | No. of patientsa |
|---|---|
| Childhood onsetb | 21 |
| Oral-esophageal Candida | 24 |
| Nail Candida | 12 |
| Skin Candida | 13 |
| Non-Candida infectionsc | 13 |
| Autoantibodiesd | 5 |
| Family history of CMC | 11 |
| AIRE1 mutationse | 2 |
A total of 24 CMC patients were included in the study.
Childhood onset occurred at ages ranging from 3 months to 7 years.
The patients had bacterial, viral, or other fungal infections but not at the time of sampling.
Five patients had parathyroid antibodies, two patients had adrenal antibodies, one patient had a thyroid antibody, one patient had a gastric parietal cell antibody, and one patient had an antinuclear antibody.
All patients were screened for the two AIRE1 mutations most common in the United Kingdom (R257* and 964del13); 1 patient was heterozygous for R257*, and one patient was homozygous for 964del13 (Simon Pearce, University of Newcastle, personal communication).