TABLE 2.

Avidity indices of mouse MAbs and humanized chimeric MAbs

Antibody	Avidity indices against PorA epitopes (M)a
	208,D-5 (anti-P1.7)	151,F-9 (anti-P1.16)	184,F-12 (anti-P1.16)
Original MAb	2.9	2.2	3.0
chIgG1	2.5 ± 0.1	1.7 ± 0.2	2.6 ± 0.1
chIgG3	2.2 ± 0.2	1.7 ± 0.2	2.2 ± 0.2
chIgM	2.1 ± 0.1	2.1 ± 0.1	1.9 ± 0.2

^aLowest concentrations of NH₄SCN resulting in a 50% reduction in absorbance in ELISA. The data are averages ± standard deviations for three independent measurements.