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Survival of the transparent and opaque phenotype variants of S. pneumoniae in the middle ears of rats following transbullar inoculation. Each data point represents the geometric mean of CFU of S. pneumoniae (± SEM) per milliliter of middle ear lavage fluid. These results are from a single experiment, with a total of four to eight middle ear samples obtained from two to four animals for each cohort (opaque and transparent), at each time point. *, P < 0.05 for the comparison.
