TABLE 6.
H. pylori genes of unknown function down-regulated ≥2-fold with decreasing medium pH with and without urea
| Avg ratio (exptl pH-Cy5-red/pH 7.4-Cy3-green)a
|
GenBank accession no. | ||||||
|---|---|---|---|---|---|---|---|
| pH 7.4
|
pH 6.2
|
pH 5.5
|
pH 4.5
|
||||
| 5 mM urea (n = 3) | 5 mM urea (n = 3) | No urea (n = 4) | 5 mM urea (n = 4) | No urea (n = 3) | 5 mM urea (n = 4) | No urea (n = 4) | |
| 1.03 | 1.00 | 0.97 | 1.09 | 1.07 | 0.99 | 0.38 | HP0022 |
| 1.04 | 1.08 | 1.20 | 1.14 | 1.05 | 0.98 | 0.39 | HP0162 |
| 1.01 | 1.08 | 1.13 | 0.98 | 1.07 | 0.73 | 0.48 | HP0234 |
| 0.91 | 0.94 | 1.04 | 0.92 | 1.27 | 0.96 | 0.29 | HP0552 |
| 0.96 | 0.86 | 0.99 | 0.78 | 0.65 | 0.86 | 0.31 | HP0707 |
| 1.03 | 0.94 | 0.98 | 0.97 | 0.76 | 0.78 | 0.35 | HP0926 |
| 0.86 | 0.96 | 1.05 | 0.91 | 0.68 | 0.79 | 0.35 | HP0946 |
| 1.01 | 0.99 | 1.10 | 0.93 | 0.95 | 1.00 | 0.35 | HP0161 |
| 0.91 | 0.97 | 0.85 | 0.80 | 0.51 | 0.62 | 0.42 | HP0270 |
| 1.07 | 0.92 | 1.11 | 0.94 | 0.67 | 0.89 | 0.48 | HP0369 |
| 0.92 | 1.10 | 1.05 | 0.91 | 0.97 | 0.89 | 0.41 | HP0582 |
| 0.94 | 0.56 | 0.31 | 0.31 | 0.35 | 0.36 | 0.20 | HP0603 |
| 1.01 | 0.96 | 0.91 | 0.69 | 0.43 | 0.73 | 0.37 | HP0838 |
| 0.92 | 0.95 | 0.84 | 0.85 | 0.65 | 0.52 | 0.44 | HP0863 |
| 0.99 | 0.75 | 0.71 | 0.78 | 0.69 | 0.41 | 0.45 | HP0864 |
| 1.17 | 1.11 | 0.99 | 0.91 | 0.94 | 0.96 | 0.47 | HP1029 |
| 0.98 | 0.98 | 1.06 | 0.93 | 0.79 | 0.88 | 0.33 | HP1106 |
| 0.97 | 1.03 | 1.21 | 0.94 | 0.93 | 1.05 | 0.38 | HP1124 |
| 1.00 | 0.94 | 0.29 | 0.63 | 0.12 | 0.32 | 0.42 | HP1217 |
| 1.09 | 0.68 | 0.43 | 0.43 | 0.37 | 0.45 | 0.45 | HP1334 |
| 1.08 | 0.91 | 0.65 | 0.59 | 0.28 | 0.64 | 0.48 | HP1377 |
| 1.02 | 0.73 | 0.88 | 0.79 | 0.41 | 0.52 | 0.31 | HP1502 |
| 0.99 | 1.00 | 1.10 | 0.92 | 0.88 | 0.97 | 0.41 | HP1546 |