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. 2003 Oct;71(10):5750–5755. doi: 10.1128/IAI.71.10.5750-5755.2003

TABLE 1.

Protection against B. abortus 544 provided to BALB/c mice by vaccination with rBLS and different adjuvant formulations

Treatment group (n = 8) Vaccine Log10 brucellae CFU (mean ± SD) at:
Log protection at:
Spleen Liver Spleen Liver
1 PBS 5.48 ± 0.13 2.45 ± 0.103 0 0
2 B. melitensis H38 3.21 ± 0.13 1.44 ± 0.136 2.27a 1.01a
3 BLS-PBS 5.11 ± 0.41 2.31 ± 0.298 0.37 0.14
4 BLS-IFA 4.23 ± 0.37 1.75 ± 0.299 1.26a 0.70a
5 BLS-MPA 4.17 ± 0.22 1.89 ± 0.482 1.31a 0.56
6 BLS-Al 4.07 ± 0.22 1.43 ± 0.088 1.40a 1.02a
7 pcDNA-BLS 3.83 ± 0.48 1.50 ± 0.398 1.61a 0.95a
a

Significantly different (P < 0.01) compared with value for control (PBS-inoculated) mice.