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. 2003 Oct;71(10):5756–5764. doi: 10.1128/IAI.71.10.5756-5764.2003

FIG. 4.

FIG. 4.

Whole-organ cytokine analysis by ELISA of spleens from mice inoculated with 1 × 102, 1 × 103, 1 × 104, 1 × 105, or 5 × 105 wild-type C. albicans organisms or with PBS (0). Whole-spleen IFN-γ and IL-4 concentrations at 72 h (A) and 1 week (B) after inoculation are indicated. The lowest points on the y axes represent the lower limits of detection of the ELISAs. Data are displayed as medians ± interquartile ranges from two experiments with six mice per group. *, P < 0.05 versus the uninfected mice; **, P < 0.05 versus values for uninfected mice and mice inoculated with 102, 103, or 104 organisms (both P values determined by the Steel test).