TABLE 1.
Splenic Th1/Th2 ratioslegend
| Inoculum (no. of organisms) | Median (25th quartile, 75th quartile) Th1/Th2 frequency ratio at indicated time postinfection
|
|||
|---|---|---|---|---|
| 12 h | 36 h | 72 h | 1 wk | |
| None | 11 (16, 8) | |||
| 102 | 10 (13, 8) | 8 (10, 6) | 8 (9, 6) | 6 (7, 5)b |
| 103 | 7 (8, 6) | 7 (9, 5) | 6 (8, 5)c | 7 (8, 6)c |
| 104 | 7 (11, 6) | 9 (32, 5) | 13 (19, 8) | 6 (7, 5)b |
| 105 | 9 (14, 8) | 11 (20, 9) | 11 (15, 10) | 5 (6, 4)b |
| 5 × 105 | 9 (20, 5) | 10 (11, 6) | 10 (12, 7) | |
legend
aRatios of frequencies of Th1 to Th2 lymphocytes harvested from the spleens of male BALB/c mice inoculated with 1 × 102, 1 × 103, 1 × 104, 1 × 105, or 5 × 105 wild-type C. albicans organisms or with PBS (None).
b
P < 0.05 versus values for uninfected mice.
c
P = 0.07 versus values for uninfected mice.