FIG. 3.

Numbers of Listeria organisms recovered from livers and spleens following systemic Listeria infection (3 × 10⁵ CFU/mouse). No significant difference was found between WT and CD18-ko mice in the numbers of Listeria organisms recovered from livers at 20 min and 6 h (a). Decreased numbers of Listeria organisms were found at 6 h in CD18-ko mouse spleens (b). At 72, 120, and 168 h, significantly reduced numbers of Listeria organisms were recovered from CD18-ko mouse livers (c) and spleens (d) compared with WT controls. Due to the difference in spleen size between WT and CD18-ko mice, numbers of Listeria organisms in spleens were normalized to 0.1 g of spleens.