Table 1.

RMS variation in coordinates (Å) between the starting x-ray structure and the minimized structure for pentamers with and without drugs

	Case	Protein	Drug
HRV-1A	Empty	0.398
	With sucrose	0.618	0.937
	With WIN54954	0.628	0.824
	With WIN56291	0.572	0.785
	With R61837	0.649	0.684
HRV-14	Empty	0.344
	With WIN52084	0.572	0.564
	With r07	0.569	0.802

Crystallographic waters and counterions were excluded from the RMS.