TABLE 1.
Kinetics of conversion to protein H-positive phenotype following injection of isolate 2109 into a mouse skin air sac
| Time postinfection (h) | No. of protein H-positive colonies/total no. (%)
|
||
|---|---|---|---|
| Blood | Spleen | Kidney | |
| 1a | 21/161 (13) | 22/48 (46) | 8/43 (19) |
| 12 | 82/149 (55) | 316/395 (80) | 28/61 (46) |
| 24 | 6/10 (60) | 196/199 (98) | 283/307 (92) |
| 48 | 13/33 (39) | 384/384 (100) | 55/59 (93) |
| 72 | 4/13 (31) | 265/265 (100) | 224/224 (100) |
Protein H-positive colonies were found as soon as 1 h postinfection, and by 24 h postinfection, >90% of colonies recovered from the organs expressed protein H.