TABLE 2.
Susceptibilities of S. pneumoniae and VS strains to amino-alcohol antimalarials
| Strain | MIC (μg/ml)a
|
||
|---|---|---|---|
| OPT | QIN | MFL | |
| S. pneumoniae R6 | 1.5 | 50 | 0.15 |
| S. pneumoniae ATCC 6303 | 0.75 | 25 | 0.15 |
| S. pneumoniae ATCC 49619 | 1.5 | 50 | 0.15 |
| S. mitis NCTC 12261 | 96 | 800 | 40 |
| S. oralis ATCC 10557 | 48 | 400 | 40 |
| S. oralis NCTC 11427 | 48 | 400 | 20 |
| S. mitis 1162/99 | 0.75 | 50 | 0.30 |
| S. mitis 1174/97 | 6 | 800 | 10 |
a
Susceptibility categorizations for OPT, QIN, and MFL: resistant, MICs of >6, >200, and >0.62 μg/ml, respectively; intermediate, MICs of 3 to 6, 100 to 200, and 0.3 to 0.6 μg/ml, respectively; susceptible, MICs of ≤1.5, ≤50, and ≤1.25 μg/ml, respectively.