TABLE 1.
Susceptibilities of 10 clinical isolates of Fusarium spp. to antifungal agents in RPMI medium (NCCLS microdilution method M-38P)
| Agent |
F. solani isolates (n = 5)
|
Non-F. solani isolates (n = 5)
|
||||||
|---|---|---|---|---|---|---|---|---|
| MIC50 | MIC90 | MFC50 | MFC90 | MIC50 | MIC90 | MFC50 | MFC90 | |
| AMB | 2a | 4 | 2 | 4 | 2 | 4 | 2 | 4 |
| 5FC | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| FLC | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| ITC | >16 | >16 | >16 | >16 | 8 | 8 | >16 | >16 |
| VRC | 4b | 8 | >16c | >16 | 1b | 1 | 8c | 8 |
| CAS | 32 | >32 | >32 | >32 | 32 | >32 | >32 | >32 |
a
Units are micrograms per milliliter throughout.
b
P = 0.09 (not significant) for VRC MICs against F. solani isolates versus those for non-F. solani Fusarium isolates.
c
P < 0.05 for VRC MFCs against F. solani isolates versus those for non-solani Fusarium isolates.